![]() Centers for Disease Control and Prevention. SARS-CoV-2 variant classifications and definitions.COVID data tracker: Variant proportions.To strengthen your protection against the virus that causes COVID-19, the CDC recommends staying up to date with COVID-19 vaccines and boosters for which you are eligible. But the COVID-19 vaccines can work to prevent severe illness. They can then spread the virus to others. People who are up to date on their vaccines can get breakthrough infections. This is an estimate from early 2023 based on genetic sequencing of samples from people with COVID-19 infections, according to the CDC. Together the omicron variants make up nearly all COVID-19 infections in the United States. Omicron has a few major offshoots, also called sublineages, branching off from B.1.1.529. But omicron seems to cause less severe disease. This variant spreads more easily than the original virus that causes COVID-19 and the delta variant. The main variant in the United States is omicron (B.1.1.529). ![]() Scientists across the world track the changes in the virus variants that cause COVID-19. If a mutation changes how a virus acts in a group of people, it's called a variant. Make medicine used to prevent or treat COVID-19 stop working or not work as well.Cause tests for the virus to be less accurate.Make the virus better at avoiding the immune system.Make the virus better at infecting a person's cells, causing serious illness.Some mutations don't have any effect on the virus.
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